Rue organic oil was well-respected by Hippocrates for its medicinal qualities. Aristotle touted ruta seed oil as calming nervousness.

Rue natural seed oil is used to relieve the pain associated with the physical symptoms of complaints such as gout, rheumatism, and sciatica. 

Ruta seed oil is effective against uncomfortable effects of gas and colic, and also to expel worms from the body. Rue seed oil is used to promote menstruation. Rue pure oil is digestive tonic and it's stimulating the appetite.